Clinical Study
Potential Applications of 68Ga-PSMA-11 PET/CT in the Evaluation of Salivary Gland Uptake Function: Preliminary Observations and Comparison with 99mTcO4− Salivary Gland Scintigraphy
Figure 1
A 55-year-old woman (patient 1) with dry mouth and a dry right eye for half a year was initially diagnosed with sjogren’s syndrome. 68Ga-PSMA-11 PET/CT MIP (a) and tomographic images (c–e) showed that the left parotid gland (SUVmax, 1.7) was smaller in volume and lower in density without 68Ga-PSMA-11 uptake than the right parotid gland (SUVmax, 9.2). SGS (b) confirmed that the uptake function of the left parotid gland was severely decreased (URleft parotid, 2.5; URrightparotid, 10.0). In addition, it was found that the 68Ga-PSMA-11 uptake of the right lacrimal gland was lower than that of the left side (SUVmaxrightlacrimal gland, 2.0; SUVmaxleftlacrimal gland, 4.2). Combined with 68Ga-PSMA-11 PET/CT and the patient’s medical history, the uptake function of the right eye was considered to be reduced. It was also found that the thyroid (f–h) density decreased with 68Ga-PSMA-11 diffuse uptake but without uptake. The patient with a history of taking supplements had a 7-year history of Hashimoto’s thyroiditis.
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