Fe-HBED Analogs: A Promising Class of Iron-Chelate Contrast Agents for Magnetic Resonance Imaging

Table 1

Relaxivity and protein binding of Fe chelates.

ID	Abbreviation	r1 (mM^−1·s^−1)	r2 (mM^−1·s^−1)	r2/r1	Protein binding (%)
Fe-1	Fe-HBED	0.49	0.52	1.06	33
Fe-2	Fe-SHBED	0.9	1.0	1.15	0
Fe-3	Fe-HBEDP	1.3	1.6	1.20	49
Fe-4	Fe-HBEDP-(CH2OH)2	0.9	1.2	1.33	20
Fe-5	Fe-HBEDP-(CH2OH)3	1.5	1.7	1.13	20