In Vivo Biokinetics of ¹⁷⁷Lu-OPS201 in Mice and Pigs as a Model for Predicting Human Dosimetry

Table 2

Time-integrated activity coefficient (TIAC (unit: h)) values for the selected organs of mice and pigs based on applied scaling methods.

	Kidney TIAC (h)		Liver TIAC (h)		Blood TIAC (h/ml)
	Mice	Pigs	Mice	Pigs	Pigs
Method 2	0.43	4.17	0.32	1.04	0.00022
Method 3	3.89	8.73	0.88	4.65	0.00025
Method 4	1.17	4.75	0.38	1.18	0.00026
Method 5	0.44	6.63	0.40	3.78	0.00021

Method 2: relative mass scaling; Method 3: time scaling; Method 4: combined relative mass and time scaling; Method 5: allometric scaling.