In Vivo Biokinetics of ¹⁷⁷Lu-OPS201 in Mice and Pigs as a Model for Predicting Human Dosimetry

Table 1

Time-integrated activity coefficient (TIAC (unit: h)) values for the selected organs of mice, pigs, and humans with respective error calculated by NUKFIT with an assumption of 10% systematic error based on Method 1 (same biodistribution approach).

	Kidney TIAC ± error (h)	Liver TIAC ± error (h)	Blood TIAC ± error (ml/h)
Method 1
Mice	1.44 ± 8.5E − 02	0.75 ± 4.1E − 02	0.0370 ± 2.0E − 03
Pigs	7.67 ± 1.8E − 01	4.08 ± 9.4E − 02	0.0002 ± 3.4E − 06
Humans	5.85 ± 4.2E − 01	5.32 ± 3.4E − 01	0.0002 ± 8.2E − 05