Empirical and Theoretical Characterization of the Diffusion Process of Different Gadolinium-Based Nanoparticles within the Brain Tissue after Ultrasound-Induced Permeabilization of the Blood-Brain Barrier

Figure 6

Example of CA distributions over time, after the CA injection. These data refer to the diffusion of Gadovist and are pictured with the black dots. In red, the Gaussian fits are shown (method I of analysis), whereas in blue are shown the distributions profiles obtained with method II, e.g., our mathematical model. By comparing, through a two-sample Kolmogorov–Smirnov test, the data shown in figure with the respective Gaussian and simulated profiles at each time point, we obtained values equal to 0.985, 0.374, 0.147, 0.047, 0.147, and 0.047 for method I and equal to 0.675, 0.675, 0.736, 0.736, 0.736, and 0.736 for method II.