Empirical and Theoretical Characterization of the Diffusion Process of Different Gadolinium-Based Nanoparticles within the Brain Tissue after Ultrasound-Induced Permeabilization of the Blood-Brain Barrier

<div>Results obtained by using the second method of evaluation of the ADCs to investigate the delivery of MultiHance within one rat brain. In (a), we show the masked CA acquired for more than 1 hour, after the BBB opening induced by ultrasound. (b) shows the results of our best fit simulation. In particular, the central slice showing the maximum CA concentration is pictured along the diffusion time. The times reported above each CA maps refer to the times elapsed after the injection of the compound.</div>

Contrast Media & Molecular Imaging

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Figure 5

Figure 5: Empirical and Theoretical Characterization of the Diffusion Process of Different Gadolinium-Based Nanoparticles within the Brain Tissue after Ultrasound-Induced Permeabilization of the Blood-Brain Barrier 

Figure 5 | Empirical and Theoretical Characterization of the Diffusion Process of Different Gadolinium-Based Nanoparticles within the Brain Tissue after Ultrasound-Induced Permeabilization of the Blood-Brain Barrier 