Empirical and Theoretical Characterization of the Diffusion Process of Different Gadolinium-Based Nanoparticles within the Brain Tissue after Ultrasound-Induced Permeabilization of the Blood-Brain Barrier

Figure 1

Experimental setup. (a) The MRI console and the computer driving the electronic for ultrasound, embedded in a tower composed by the water degassing system, the motor control, and the ultrasound generator. (b) The transducer and its electronic compatible with the MRI scanner. The transducer can move along the two perpendicular directions pictured by the green arrows. (c) The respiration and the temperature probes for real-time monitoring of the animal’s vital signs.