Research Article

Imaging Fibrogenesis in a Diet-Induced Model of Nonalcoholic Steatohepatitis (NASH)

Table 2

Liver uptake of [18F]FtRGD in mice fed with CDAHDF, HFD, and standard diet-fed mice (n = 5 per group). All data are presented as mean ± SD, and statistical significance is shown as , , and .

DaysStandard diet
%ID/g ± SD
High fat diet
%ID/g ± SD
CDAHFD
%ID/g ± SD

210.52 ± 0.130.50 ± 0.190.64 ± 0.11
280.54 ± 0.160.62 ± 0.180.72 ± 0.19
350.46 ± 0.11$0.56 ± 0.130.70 ± 0.10
420.57 ± 0.09$0.60 ± 0.160.74 ± 0.11
490.47 ± 0.11$$0.52 ± 0.080.84 ± 0.11
560.53 ± 0.09$$0.52 ± 0.080.90 ± 0.10
630.48 ± 0.14$$0.48 ± 0.110.88 ± 0.13
720.57 ± 0.10$$0.51 ± 0.090.96 ± 0.15