Prediction of Overall Survival and Progression-Free Survival by the ¹⁸F-FDG PET/CT Radiomic Features in Patients with Primary Gastric Diffuse Large B-Cell Lymphoma

Table 3

Univariate analysis (computed tomography).

	OS		PFS
	HR (95%CI)	value	HR (95%CI)	value
B Symptom (yes vs. no)	0.257 (0.042–1.562)	0.140	0.213 (0.047–0.967)	0.045
Histogram based
Kurtosis (≥101.9046 vs.<101.9046)	8.399 (1.382–51.043)	0.021	6.028 (1.091–33.300)	0.039
Shape based
Volume (≥47.5887 vs.<47.5887)	10.139 (1.131–90.883)	0.038	6.426 (1.245–33.166)	0.026
Sphericity (≥0.6407 vs.<0.6407)	6.679 (0.746–59.808)	0.090	10.157 (1.222–84.413)	0.032
GLRLM
HGRE (≥10445.0192 vs.<10445.0192)	6.222 (0.684–56.586)	0.105	9.216 (1.098–77.335)	0.041
LRHGE (≥16855.0511 vs.<16855.0511)	8.867 (0.985–79.830)	0.052	5.603 (1.081–29.032)	0.040
GLNU (≥880.6339 vs.<880.6339)	12.972 (1.448–116.210)	0.022	8.049 (1.558–41.576)	0.013
RLNU (≥4739.7637 vs.<4739.7637)	10.139 (1.131–90.883)	0.038	6.426 (1.245–33.166)	0.026
GLZLM
LZE (≥3642.5187 vs.<3642.5187)	6.020 (1.003–36.139)	0.050	5.140 (1.143–23.106)	0.033
HGZE (≥10539.0008 vs.<10539.0008)	7.330 (1.202–44.687)	0.031	6.181 (1.365–27.976)	0.018
LZLGE (≥0.4211 vs.<0.4211)	7.216 (1.190–43.764)	0.032	6.284 (1.395–28.312)	0.017
LZHGE (≥38755329.6111 vs.<38755329.6111)	6.020 (1.003–36.139)	0.050	5.140 (1.143–23.106)	0.033
GLNU (≥90.9505 vs.<90.9505)	10.139 (1.131–90.883)	0.038	6.426 (1.245–33.166)	0.026
ZP (≥0.1439 vs.<0.1439)	0.227 (0.037–1.385)	0.108	0.195 (0.043–0.885)	0.034

HGRE, high gray-level run emphasis; LRHGE, long-run high gray-level emphasis; GLNU, gray-level non-uniformity; RLNU, run length nonuniformity; LZE, long-zone emphasis; HGZE, high gray-level zone emphasis; LZLGE, long-zone low gray-level emphasis; GLRLM, gray-level run length matrix; GLZLM, gray-level zone-length matrix; LZHGE, long-zone high gray-level emphasis; ZP, zone length nonuniformity zone percentage; PFS, progression-free survival; OS, overall survival; HR, hazard ratio; CI, confidence interval. Asterisk () indicates significance with a value of <0.05 (shown in bold).