Assessment of the Relaxation-Enhancing Properties of a Nitroxide-Based Contrast Agent TEEPO-Glc with In Vivo Magnetic Resonance Imaging

Figure 2

TEEPO-Glc cytotoxicity in vitro. Cell viability study with (a) HeLa cells (reproduced from Ref. 35 with permission from The Royal Society of Chemistry) and (b) HUVECs were determined by CellTiter-Glo® assay kit (ATP measurement), and the results (mean ± SD, ) were compared with untreated control cells whose viability was set at 100%. LDH release study with (c) HeLa cells and (d) HUVECs. Control cells were lysed with LDH assay lysis solution and set at 100% (lysis). The level of significance was set at a probability of () when compared with untreated control cells (Kruskal–Wallis with Dunnett’s test).

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