Preclinical Imaging Biomarkers for Postischaemic Neurovascular Remodelling

Figure 9

(a) [¹⁸F]GP1 PET image of cynomolgus monkeys with arterial and venous catheters that were inserted in the right carotid artery and vena cava, respectively (maximum-intensity projection 0–60 min). Both arterial and venous thrombi exhibited tracer uptake. (b) [¹⁸F]GP1 time-activity curves of thrombus uptake and blood clearance in monkeys 1 (displayed in (a)) and 2. [¹⁸F]GP1, [¹⁸F]glycoprotein-1; PET, positron emission tomography; M1, monkey 1; M2, monkey 2; %ID/g, percentage injected dose per gram. This research was originally published by Lohrke et al. [101].

(a)

(b)