Histogram Analysis and Visual Heterogeneity of Diffusion-Weighted Imaging with Apparent Diffusion Coefficient Mapping in the Prediction of Molecular Subtypes of Invasive Breast Cancers

Table 1

Comparison of the average values of apparent diffusion coefficient (ADC) (mm²/s) on histogram analysis according to receptor status.

	ER+	ER−		PR+	PR−		HER2+	HER2−
Mean	1.11	1.20	0.096	1.12	1.18	0.232	1.25	1.12	0.034
Perc10	0.82	0.90	0.113	0.82	0.89	0.137	0.92	0.60	0.101
Perc50	1.09	1.19	0.095	1.10	1.17	0.223	1.23	1.10	0.046
Perc90	1.43	1.54	0.142	1.45	1.51	0.424	1.62	1.43	0.040
SD	0.24	0.25	0.603	0.24	0.24	0.866	0.27	0.23	0.165
Kurtosis	3.26	3.22	0.888	3.22	3.28	0.828	3.30	3.23	0.815
Skewness	0.33	0.24	0.505	0.31	0.29	0.871	0.29	0.30	0.944

ER: estrogen receptor; HER2: human epidermal growth factor receptor 2; Perc: percentile; PR: progesterone receptor; SD: standard deviation.