Early Prediction of Treatment Response of Neuroendocrine Hepatic Metastases after Peptide Receptor Radionuclide Therapy with ⁹⁰Y-DOTATOC Using Diffusion Weighted and Dynamic Contrast-Enhanced MRI

Figure 6

DCE-MRI evaluation results for (a, b), K_trans (c), k_ep (d), and iAUC (e) and the three classes of lesions (light grey: regressive; dark grey: stable; red: progressive). The plots in (a) shows the variation of over 10 weeks after therapy (from T₁ to T₃) with significant differences for regressive vs stable () and regressive vs progressive lesions (; asterisks). The graphs in (b–e) demonstrate the variation of the four parameters over time, indicating a significant increase of in regressive lesions as compared with the two other groups at T₃ (b), but no significant differences in behavior between the three classes of lesions for K_trans (c), k_ep (d), and iAUC (e).

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