Research Article

Evaluating Hepatobiliary Transport with 18F-Labeled Bile Acids: The Effect of Radiolabel Position and Bile Acid Structure on Radiosynthesis and In Vitro and In Vivo Performance

Figure 4

Time-activity curves (TACs) of 3α-[18F]FCA, 3β-[18F]FCA, 3β-[18F]FGCA, and 3β-[18F]FCDCA in liver (red curve) and gallbladder and intestines (GBI; green curve) of wild-type mice. Uptake of the tracers was expressed as % injected dose (% ID) and normalized for a 20 g mouse. Data are mean ± SD ( per group).