Evaluating Hepatobiliary Transport with ¹⁸F-Labeled Bile Acids: The Effect of Radiolabel Position and Bile Acid Structure on Radiosynthesis and In Vitro and In Vivo Performance

Figure 3

Graphs of the concentration dependent decrease in uptake of tritium labeled substrate ([³H]TC for NTCP and BSEP; [³H]EbG for OATP1B1). IC50s of the compounds were determined by GraphPad, and their respective Ki-values can be found in Table 2. All data are mean ± SD ().