Tumor-Shed Antigen Affects Antibody Tumor Targeting: Comparison of Two 89Zr-Labeled Antibodies Directed against Shed or Nonshed Antigens

<div>Representative autoradiography images of 89Zr-labeled antibody. 89Zr-amatuximab (2.96 MBq) coinjected with (a) 10 µg and (b) 60 µg amatuximab; 89Zr-B3 (2.22 MBq) coinjected with (c) 15 µg and (d) 60 µg B3 mAb.</div>

Contrast Media & Molecular Imaging

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Figure 5

Figure 5: Tumor-Shed Antigen Affects Antibody Tumor Targeting: Comparison of Two 89Zr-Labeled Antibodies Directed against Shed or Nonshed Antigens