Spectral Photon-Counting Molecular Imaging for Quantification of Monoclonal Antibody-Conjugated Gold Nanoparticles Targeted to Lymphoma and Breast Cancer: An <i>In Vitro</i> Study

<div>(a) SKBR3 cell line phantom. SKBR3 cells with Herceptin-AuNPs show more volume, indicating more gold is present. Material decomposition basis images show Au (yellow/orange, the hue represents the concentration), lipids (pink), and water-like material (grey). (b) Raji cell line phantom; Raji cells with rituximab-AuNPs show more volume and brighter hue, indicating a high concentration of gold present.</div>

Contrast Media & Molecular Imaging

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Figure 3: Spectral Photon-Counting Molecular Imaging for Quantification of Monoclonal Antibody-Conjugated Gold Nanoparticles Targeted to Lymphoma and Breast Cancer: An <i>In Vitro</i> Study 

Figure 3 | Spectral Photon-Counting Molecular Imaging for Quantification of Monoclonal Antibody-Conjugated Gold Nanoparticles Targeted to Lymphoma and Breast Cancer: An In Vitro Study 