Review Article

Targeted Optical Imaging Agents in Cancer: Focus on Clinical Applications

Figure 3

In vivo optical imaging with folate. Chemical structure is shown of folate labeled with (a) FITC (abs = 490 nm, em = 525 nm), known as EC17, and (b) ICG (abs = 783 nm, em = 813 nm), known as OTL38. (c) White light laparoscopic image of peritoneum in vivo and corresponding (d) fluorescence image show enhanced contrast from ovarian cancer metastases following systemic administration of EC17 ((c) and (d) reprinted with the permission from [60]).
(a)
(b)
(c)
(d)