Research Article

Impact of Perinatal Exposure to SARS-CoV-2 Infection on Early Health Outcomes among Infants Born from 2020 to 2021 in British Columbia, Canada

Table 2

Healthcare resource utilization and reason for emergency department visit or hospitalization in the first 12 months after birth among infants with and without perinatal exposure to SARS-CoV-2.

Infants in exposed cohort (n = 480)Infants in non‐exposedcohort (n = 1904)Odds ratio (95% CI)

≥1 emergency department visit81 (16.88%)246 (12.92%)1.40 (1.05, 1.85)
 Nausea and/or vomiting13 (2.71%)32 (1.68%)
 Feeding difficulties in newborn9 (1.88%)16 (0.84%)
 Fever9 (1.88%)33 (1.73%)
 Rash8 (1.67%)10 (0.53%)
 Inconsolable crying7 (1.46%)24 (1.26%)
 Shortness of breath7 (1.46%)24 (1.26%)
 Neonatal jaundice6 (1.25%)29 (1.52%)
≥1 hospitalization39 (8.13%)98 (5.15%)1.63 (1.11, 2.41)
 Neonatal jaundice9 (1.89%)29 (1.52%)
 Transient tachypnoea of the newborn<55 (0.26%)
 Urinary tract infection<5<5
 COVID-19<5<5

n values < 5 not reported. The effect estimate for all outcomes was obtained by comparing exposed vs. non‐exposed cohorts. Significant odds ratio (i.e., does not cross 1.0 in 95% CI).