Impact of Perinatal Exposure to SARS-CoV-2 Infection on Early Health Outcomes among Infants Born from 2020 to 2021 in British Columbia, Canada

Table 1

Characteristics of infants born to mothers with a positive SARS-CoV-2 test (exposed cohort) and to mothers without (non‐exposed cohort).

	Infants in exposed cohort (n = 480)	Infants in non-exposedcohort (n = 1904)	Mean difference or odds ratio (95% CI)^†
Sex (male); n (%)	262 (54.58%)	1037 (54.46%)
Birthplace (hospital); n (%)	475 (99.20%)	1884 (99.16%)
Gestational age (weeks); mean (SD)	38.51 (1.69)	38.66 (1.48)
Preterm (<37 weeks GA); n (%)	44 (9.17%)	122 (6.41%)	1.79 (1.09, 2.92)
Birth weight (grams); mean (SD)	3267.21 (536.39)	3336.62 (501.66)	−66.24 (−111.63, −20.86)
Small-for-gestational age; n (%)	49 (10.21%)	163 (8.56%)	1.22 (0.87, 1.71)
Apgar score at 5 min; mean (SD)	8.90 (0.73)	8.90 (0.75)	−0.00 (−0.07, 0.07)
Maternal residence (rural); n (%)	26 (5.42%)	76 (3.99%)	1.49 (0.86, 2.56)

Only 480 out of 484 cases had matched controls. Matching variable. ^†The effect estimate for all outcomes was obtained by comparing exposed vs. non‐exposed cohorts. The effect estimate in the conditional logistic regression model (for binary outcomes) was presented as odds ratio (OR). The effect estimate in the linear mixed effect model (for continuous outcomes) was presented as regression coefficient (mean difference between the two groups).