Research Article

Antimicrobial Therapy as a Risk Factor of Multidrug-Resistant Acinetobacter Infection in COVID-19 Patients Admitted to the Intensive Care Unit

Table 3

Basic characteristics of the patients.

VariableMDR-Ab infectionNo MDR-Ab infection

Quantitative variablesMedian (25th percentile, 75th percentile)
 Age (years)66 (56, 70)64 (50, 70)
 C-reactive protein (mg/L)130 (76, 170)112 (65, 149)
 Glomerular filtration rate (ml/s)1.32 (0.87, 1.59)1.24 (0.96, 1.48)
 Neutrophil count (×1000 cells/ml)7.45 (4.85, 13.29)7.69 (4.46, 12.04)
 Lymphocyte count (×1000 cells/ml)0.74 (0.48, 1.34)0.79 (0.54, 1.36)
 CD4+ lymphocyte count (cells/ml)285 (180, 462)300 (160, 430)
 Length of ICU stay13 (6, 18)6 (4, 9)

Categorical variablesn/n total (%)
 Diabetes mellitus13/33 (39.39%)19/57 (33.33%)
 Obesity19/33 (57.58%)38/57 (49.12%)
 Male gender21/33 (63.63%)36/57 (63.16%)
 Tocilizumab therapy13/33 (39.39%)7/57 (12.28%)
 Previous exposure to ceftriaxone20/33 (60.60%)17/57 (29.82%)
 Previous exposure to meropenem6/33 (18.18%)9/57 (15.78%)
 Mechanical ventilation20/33 (60.60%)22/57 (38.60%)
 Death17/33 (51.52%)21/57 (36.84%)

in univariate analysis. ICU: intensive care unit; MDR-Ab: multidrug-resistant Acinetobacter.