Research Article
Analyzing Trends in Demographic, Laboratory, Imaging, and Clinical Outcomes of ICU-Hospitalized COVID-19 Patients
Table 3
Association between demographic and primary clinical data with outcome.
| | Variable | Outcome | Total | value | | Good clinical outcome | Worse clinical outcome |
| | Sex, F (%) | Male | 132 (58.40) | 92 (55.76) | 224 | 0.601 | | Female | 94 (41.60) | 73 (44.24) | 167 |
| | Age, F (%) | ≤60 | 108 (47.78) | 48 (29.09) | 156 | <0.0001 | | >60 | 118 (52.22) | 117 (70.91) | 235 |
| | Comorbidity, F (%) | Diabetes | Yes | 58 (25.66) | 98 (59.39) | 156 | <0.0001 | | Hypertension | 70 (30.98) | 92 (55.76) | 162 | <0.0001 | | Ischemic heart disease | 41 (18.14) | 41 (24.85) | 82 | 0.108 | | Dyslipidemia | 15 (6.63) | 23 (13.97) | 38 | 0.024 | | CKD | 34 (15.04) | 47 (28.48) | 81 | 0.001 | | COPD | 27 (11.94) | 27 (16.36) | 54 | 0.211 | | Hypothyroidism | 5 (2.22) | 4 (2.42) | 9 | 0.573 | | Rheumatoid arteritis | 1 (0.44) | 1 (0.60) | 2 | 0.669 | | Brain hemorrhage | 1 (0.44) | 22 (13.33) | 23 | <0.0001 | | Parkinson | 1 (0.44) | 2 (1.21) | 3 | 0.422 | | Seizure | 6 (2.66) | 3 (1.82) | 9 | 0.739 | | CVA | 10 (4.42) | 30 (18.19) | 40 | <0.0001 | | Sickle cell | 1 (0.44) | 1 (0.60) | 2 | 0.667 | | ESRD | 14 (6.20) | 10 (6.06) | 24 | 0.956 | | Cancer | 2 (0.88) | 10 (6.06) | 12 | 0.004 | | Trauma | 0 | 3 (1.82) | 3 | 0.074 | | LAM | 0 | 1 (0.60) | 1 | 0.422 | | MS | 1 (0.44) | 1 (0.60) | 2 | 0.578 | | Cirrhosis | 3 (1.32) | 2 (1.21) | 5 | 0.645 | | IPF | 2 (0.88) | 5 (3.03) | 7 | 0.117 |
| | O2 saturation ranges at baseline, F (%) | O2 < 88% | 169 (74.78) | 147 (89.09) | 316 | 0.002 | | 92% > O2 ≥ 88% | 44 (19.47) | 15 (9.09) | 59 | | O2 ≥ 92% | 13 (5.75) | 3 (1.82) | 16 |
| | The score of lung involvement at baseline, F (%) | 0–8 | 50 (22.12) | 31 (18.79) | 81 | 0.002 | | 9–16 | 110 (48.68) | 56 (33.94) | 168 | | 17–25 | 66 (22.20) | 78 (47.27) | 142 |
| | Laboratory findings at baseline | CRP, F (%) | − | 45 (19.91) | 33 (20) | 78 | 0.981 | | + | 43 (19.02) | 34 (20.60) | 77 | | ++ | 77 (34.08) | 54 (32.73) | 131 | | +++ | 61 (26.99) | 44 (26.67) | 105 | | ESR | Mean ± SD | 44.22 ± 28.21 | 48.56 ± 29.52 | 391 | 0.142 | | CPK | 408.98 ± 710.90 | 378.68 ± 632.60 | 391 | 0.663 | | LDH | 702.28 ± 436.34 | 723.87 ± 382.47 | 391 | 0.611 | | WBC | 8.80 ± 5.45 | 9.91 ± 5.70 | 391 | 0.051 | | NLR | 9.49 ± 8.71 | 11.62 ± 8.46 | 391 | 0.016 | | BUN | 57.23 ± 58.84 | 66.13 ± 40.08 | 391 | 0.094 | | Cr | 1.76 ± 2.25 | 1.76 ± 1.24 | 391 | 0.981 | | PLT | 205.42 ± 96.94 | 200.72 ± 84.50 | 391 | 0.617 | | AST | 75.78 ± 171.04 | 65.90 ± 65.95 | 391 | 0.481 | | ALT | 70.19 ± 160.57 | 55.42 ± 60.45 | 391 | 0.261 | | ALP | 204.62 ± 107.43 | 229.40 ± 138.54 | 391 | 0.047 |
| | SpO2 at baseline | Mean ± SD | 80.65 ± 10.32 | 73.96 ± 12.04 | 391 | <0.0001 |
| | ICU length of stay | Mean ± SD | 9.99 ± 6.33 | 12.22 ± 12.41 | 391 | 0.021 |
| | Hospital length of stay | Mean ± SD | 11.83 ± 6.22 | 14.31 ± 12.33 | 391 | 0.010 |
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hi-square test ,student’s t-test. |
