Circulating Dynamics of SARS-CoV-2 Variants between April 2021 and February 2022 in Turkey

Table 1

Spike mutation pattern according to lineage and variants of SARS-CoV-2 strains circulating in Turkey.

Lineages	Spike mutation patterns	CoV-RDB, n (%)
B.1.1.7/Alpha		205 (42)
	∆69–70, ∆144, N501Y	161 (79)
	∆69–70, ∆144, N501Y, A570D, D614G, P681H, T716I	7 (3)
	∆69–70, S98F, ∆144, and N501Y	6 (4)
	∆144 and N501Y	5 (3)
	∆69–70, ∆144, N501Y, A570D, D614G, P681H, S704L, T716I, and	4 (2)
	N501Y	3 (1)
	∆69–70, ∆144, G181V, and N501Y	3 (1)
	∆69–70, ∆144, V289L, and N501Y	3 (1)
	∆69–70, ∆144, S155R, F374S, and N501Y	3 (1)
	∆69–70, ∆144, S155R, and N501Y	2 (1)
	∆69–70, L141F, ∆144, and N501Y	2 (1)
	∆69–70, ∆142, Y144V, and N501Y	2 (1)
	A67V, ∆69–70, ∆144, and N501Y	1 (0.5)
	∆69–70, ∆144, A260V, and N501Y	1 (0.5)
	∆69–70 and N501Y	1 (0.5)
	S98F, ∆144 and N501Y	1 (0.5)
B.1.351/Beta		11 (2)
	D80A, D215G, ∆241–243, K417N, E484K, and N501Y	6 (100)
B.1.617/Delta		82 (16)
	T95I, G142D, ∆156–157, R158G, L452R, T478K, D614G, P681R, and D950N	27 (33)
	T95I, G142D, ∆156–157, R158G, L452R, and T478K	9 (11)
	G142D, ∆156–157, R158G, L452R, and T478K	7 (9)
	G142D, ∆156–157, R158G, L452R, T478K, D614G, P681R, and D950N	6 (7)
	T95I, G142D, ∆156–157, R158G, L452R, T478K, D614G, P681R, D950N, and E1202Q	3 (4)
	K41X, T95I, G142D, Δ156–157, R158G, L452R, T478K, D614G, P681R, and D950N	3 (4)
	G142D, ∆156–157, R158G, A222V, L452R, and T478K	3 (4)
	T95I, G142D, ∆156–157, R158G, L452R, T478K, D614G, P681R, D950N, A1020V, and	2 (3)
	A222V	2 (3)
	G142D, ∆156–157, R158G, W258R, L452R, T478K, D614G, P681R, and D950N	2 (3)
	T95I, G142D, ∆156–157, R158G, L452R, T478K, D614G, P681R, D950N, and H1159R	2 (3)
	G142D, ∆156–157, R158G, N440T, and L452R	1 (1)
	L452R and N501Y	1 (1)
	T478K	1 (1)
	C136F, ∆144, A222V, ∆242–243, L452R, T478R, and E484Q	1 (1)
	K77T, G142D, ∆156–157, R158G, L452R, and T478K	1 (1)
	T95I, G142D, ∆156–157, R158G, L452R, T478K, D614G, P681R, D950N, and V1228L	1 (1)
	T95I, G142D, ∆156–157, R158G, L452R, T478K, D614G, P681R, D950N, and F1075L	1 (1)
	T95I, G142D, ∆156–157, R158G, L452R, T478K, D614G, P681R, D950N, and V1104L	1 (1)
	T95I, G142D, Δ156–157, R158G, L452R, T478K, D614G, P681R, D950N, and E1202Q	1 (1)
	G142D, ∆156–157, R158G, L452R, T478K, D614G, P681R, D950N, and M1237I	1 (1)
	T95I, G142D, ∆156–157, R158G, A352V, L452R, T478K, D614G, P681R, N777D, and D950N	1 (1)
	G142D, Δ156–157, R158G, T385I, L452R, T478K, D614G, P681R, D950N, and H1159R	1 (1)
	T95I, G142D, ∆156–157, R158G, L452R, T478K, D614G, P681R, D950N, and I850L	1 (1)
	V42X, T95I, G142D, Δ156–157, R158G, E224Q, L452R, T478K, D614G, P681R, A688V, I850L, M869V, and D950N	1 (1)
	V831, T95I, G142D, Δ156–157, R158G, L452R, T478K, D614G, P681R, and D950N	1 (1)
	Δ156–157, R158G, T478K, D614G, P681R, and S1161SAPT	1 (1)
B.1.525/Eta		4 (1)
	A67V, ∆69–70, ∆144, and E484K	1 (25)
	A67V, ∆69–70, ∆144, and N5017	1 (25)
	Q52R, A67V, ∆69–79, ∆144, and E484K	1 (25)
	Q52R, A67V, ∆69–79, ∆144, S22IL, and E484K	1 (25)
P.2/Zeta		4 (0.8)
	D138Y L178I, S477N, A522S, D614G, Q675R, and A845S	2 (50)
	T95I, ∆144, and E484K	1 (50)
B.1.526/VOI lota		1 (0.2)
	F157S and A520S	1 (100)
B.1.1.529/Omicron		28 (6)
	S45X, A67V, Δ69–70, T95I, G142D, Δ143–145, N211I, Δ212, R214R_EPE, G339D, R346K, S371F, S373P, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, and L981F	17 (60)
	A67V, Δ69–70, T95I, G142D, Δ143–145, N211I, Δ212, 5214R_EPE, G339D, S371F, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, and L981F	9 (32)
	V70X, T95I, G142D, Δ143–145, N211I, Δ212, R214R_EPE, G339D, S371F, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, N796Y, N856K, Q954H, N969K, and L981F	1 (4)
	MIK, Δ3-50, D531, F55S, L56F, P57T, A67V, Δ69-70, G142D, Δ143–145, N211I, Δ212, R214X_EPE, Q218H, G339D, S371F, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, and L981F	1 (4)
BA.1/Omicron		79 (16)
	S45X, A67V, Δ69–70, T95I, G142D, Δ143–145, N211I, Δ212, R214R_EPE, G339D, R346K, S371F, S373P, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, and L981F	79 (100)
Wild type, no mutation		78 (16)
Total		492 (100)

CoV-RDB: Stanford coronavirus antiviral and resistance database.