Research Article

The Viral Load of Human Cytomegalovirus Infection in Children following Hematopoietic Stem Cell Transplant by Chip Digital PCR

Table 2

Characteristics of 125 children following HSCT.

Children patient characteristicsNo. of children patients (no. of HCMV Positive)

Age (years)0–670 (17)
7–1243 (17)
≥1212 (4)

SexMale73 (22)
Female52 (16)

HCMV IgGD+ & R+68 (28)
D+ & R-31 (7)
D & R+18 (3)
D & R-5 (0)

DiseaseAML37 (15)
ALL17 (7)
AA22 (5)
MDS10 (4)
Lymphoma3 (1)
NB5 (0)
WAS6 (1)
MPS25 (5)

HSCTAllogeneic122 (38)
Autologous3 (0)

Source of HSCTBM + PBSCT98 (32)
PBSCT18 (3)
UCB-HSCT9 (3)

GVHD (grade)083 (23)
1-230 (12)
3-412 (3)

Abbreviations: HSCT, hematopoietic stem cell transplantation; HCMV, human cytomegalovirus; D, donor patients; R, recipient patients; AML, acute myelocytic leukemia; ALL, acute lymphocytic leukemia; AA, aplastic anemia; MDS, myelodysplastic syndrome; NB, neuroblastoma; WAS, Wiskott–Aldrich syndrome; MPS, mucopolysaccharidosis; BM, bone marrow; PBHSCT, peripheral blood stem cell transplantation; GVHD, graft vs. host disease.