Molecular Assessment of Domain I of Apical Membrane Antigen I Gene in Plasmodium falciparum: Implications in Plasmodium Invasion, Taxonomy, Vaccine Development, and Drug Discovery

Table 6

Pairwise comparison of protein sequences of Domain I of AMA1 across human Plasmodium species using the pairwise sequence alignment EMBOSS Needle tool.

Human Plasmodium species pairs	% identity	Scores
Pf/PV	54	466
Pf/Pm	50	445
Pf/Po	43	389
Pf/Pk	50	430
Pv/Pm	70	607
Pv/Po	70	607
Pv/Pk	83	693
Pm/Po	70	598
Pm/Pk	69	578
Po/Pk	72	612

Pf = Plasmodium falciparum; Pv = Plasmodium vivax; Pm = Plasmodium malariae; Po = Plasmodium ovale; Pk = Plasmodium knowlesi.