Canadian Journal of Infectious Diseases and Medical Microbiology

Research Article

Multidrug-Resistant Escherichia coli Causing Urinary Tract Infections among Controlled and Uncontrolled Type 2 Diabetic Patients at Laquintinie Hospital in Douala, Cameroon

Table 5

Biochemical abnormalities as function of diabetic status and E. coli infection.


Biochemical parameters		Nondiabetics 346 (%)		Diabetics with balanced blood glucose 226 (%)		Diabetics with unbalanced blood glucose levels 279 (%)		value
Biochemical parameters		Yes 14 (4.04%)	No 332 (95.95%)	Yes 36 (15.92%)	No 190 (84.07%)	Yes 75 (26.88%)	No 204 (73.11%)	value
Escherichia coli

HbA1C	HbA1C abnormal	0 (0%)	0 (0%)	0 (0%)	0 (0%)	75 (100%)	204 (100%)	<0.001
HDL	Hypocholesterolemia HDL	4 (28.57%)	49 (14.75%)	24 (66.66%)	128 (67.36%)	43 (57.33%)	139 (68.13%)	<0.001
Artherogenicity index total cholesterol/HDL-cholesterol	Double risk	5 (35.71%)	30 (9.03%)	23 (63.88%)	90 (47.36%)	45 (60%)	135 (66.17%)	<0.001
LDL	Hypercholesterolemia LDL	0 (0%)	4 (1.20%)	8 (22.22%)	72 (37.89%)	51 (68%)	103 (50.49%)	0.001
Triglyceride	Hypertriglyceridemia	0 (0%)	41 (12.34%)	18 (50%)	69 (36.31%)	51 (68%)	105 (51.47%)	0.001
Total cholesterol	Total hypercholesterolemia	0 (0%)	2 (0.60%)	7 (19.44%)	30 (15.78%)	32 (42.66%)	92 (45.04%)	0.01
Urea	Hyperuremia	0 (0%)	18 (5.42%)	12 (33.33%)	25 (13.15%)	15 (20%)	17 (8.33%)	0.02
Creatinine clearance	Moderate renal failure	3 (21.42%)	10 (3.01%)	5 (13.88%)	30 (15.78%)	27 (36%)	47 (23.03%)	0.001
Creatinine clearance	End-stage renal failure	0 (0%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)	1 (0.49%)	0.001
Creatinine	Hypercreatininemia	0 (0%)	1 (0.30%)	1 (2.77%)	16 (8.42%)	26 (34.66%)	33 (16.17%)	0.002
Creatinine	Hypocreatininemia	0 (0%)	9 (2.71%)	0 (0%)	1 (0.52%)	0 (0%)	3 (1.47%)	0.002
ALAT	Hyper ALAT	1 (7.14%)	20 (6.02%)	2 (5.55%)	25 (13.15%)	10 (13.33%)	26 (12.74%)	0.030
ALAT	Hypo ALAT	0 (0%)	5 (1.5%)	1 (2.77%)	0 (0%)	0 (0%)	0 (0%)	0.030
ASAT	Hyper ASAT	0 (0%)	1 (0.30%)	2 (5.55%)	6 (3.15%)	11 (14.66%)	13 (6.37%)	<0.001
ASAT	Hypo ASAT	0 (0%)	3 (0.90%)	1 (2.77%)	0 (0%)	0 (0%)	0 (0%)	<0.001
Glycemia	Hyperglycemia	0 (0%)	0 (0%)	0 (0%)	0 (0%)	75 (100%)	204 (100%)	<0.001
Proteinuria	Positive	6 (42.85%)	39 (11.74%)	22 (61.11%)	55 (28.94%)	41 (54.66%)	42 (20.58%)	0.73
Uricemia	Hypouremia	1 (7.14%)	37 (11.14%)	10 (27.77%)	62 (32.63%)	15 (20%)	40 (19.6%)	0.002
K⁺	Hyperkaliemia	4 (28.57%)	59 (17.77%)	7 (19.44%)	6 (3.15%)	5 (6.66%)	7 (3.43%)	0.94
K⁺	Hypokaliemia	0 (0%)	60 (18.07%)	13 (36.11%)	53 (27.89%)	20 (26.66%)	62 (30.39%)	0.94
CL⁻	Hyperchloremia	0 (0%)	9 (2.71%)	16 (44.44%)	76 (40%)	29 (38.66%)	74 (36.27%)	0.003
CL⁻	Hypochloremia	0 (0%)	3 (0.90%)	0 (0%)	7 (3.68%)	5 (6.66%)	6 (2.94%)	0.003
Na⁺	Hypernatremia	5 (35.71%)	126 (37.95%)	18 (50%)	32 (16.84%)	14 (18.66%)	28 (13.72%)	0.01
Na⁺	Hyponatremia	0 (0%)	8 (2.40%)	0 (0%)	9 (4.73%)	6 (8%)	7 (3.43%)	0.01
CRP	Hyper CRP	14 (21.42%)	50 (15.06%)	34 (94.44%)	49 (25.78%)	63 (84%)	83 (40.68%)	0.003
LDL-cholesterol/HDL-cholesterol	Abnormal	0 (0%)	5 (1.50%)	17 (47.22%)	95 (50%)	46 (61.33%)	102 (50%)	0.002

ALAT: alanine aminotransferase; ASAT: aspartate aminotransferase; CRP: C-reactive protein; LDL: low-density lipoproteins; HDL: high-density lipoproteins; HbA1C: glycated haemoglobin.