Portal hypertension refers to a hepatic venous pressure gradient of more than 5 mmHg. It often leads to some severe complications, such as gastroesophageal variceal bleeding, ascites, splenomegaly, and hypersplenism. Numerous researches have greatly improved our understanding regarding pathogenesis and management of portal hypertension. Nowadays, Baveno VI consensus workshop has proposed an emerging concept regarding risk stratification and individualized care for patients with portal hypertension. More recently, the American Association for the Study of Liver Diseases (AASLD) Practice Guidance has summarized the risk stratification, diagnosis, and management of portal hypertensive bleeding more deeply. However, as clearly indicated by the Baveno VI consensus and AASLD practice guidance, lots of issues remain unresolved.

We invite the researchers to contribute original research articles and review articles to explore the diagnosis and management of portal hypertension. We are particularly interested in high-quality systematic reviews and meta-analyses in this field.

Potential topics include but are not limited to the following:

• Noninvasive diagnosis of portal hypertension and gastroesophageal varices
• Natural history and management of portal vein thrombosis in liver cirrhosis
• Therapeutic strategy of noncirrhotic portal hypertension, including idiopathic noncirrhotic portal hypertension, Budd-Chiari syndrome, and extrahepatic portal vein obstruction
• Reassessment of timing of drug and endoscopic therapy for the management of variceal bleeding in liver cirrhosis
• Refining the indications for transjugular intrahepatic portosystemic shunt for portal hypertension related complications