Review Article

Chronic Liver Disease in Ethiopia with a Particular Focus on the Etiological Spectrums: A Systematic Review and Meta-Analysis of Observational Studies

Table 3

The overall summary of reported frequencies of CLD etiologies in the primary studies included in this review, Ethiopia, 2021.

First author [reference]Sample sizeHepatitis B virusHepatitis C virusHepatosplenic schistosomiasisCo-hepatitis B and C virusCo-hepatitis B and D virusVisceral leishmaniasisHIVAlcoholNAFLDWilson’s diseaseAutoimmune hepatitisBiliary cirrhosisAlcohol plus HBVAlcohol plus HCVUnidentified

Muhie [24]2483NRNRNRNRNR40.01NRNRNRNRNR
Adhanom and Desalegn [25]1175521NR3NRNRNR2NRNRNRNRNRNR51
Ayele and Gebre-Selassie [26]1204327NR3NRNRNRNRNRNRNRNRNRNRNR
Gaddisa Desu [27]96307NR1NRNRNR20NRNRNRNR2144
Taye et al. [28]57880a8bNRNRNRNRNRNRNRNRNRNRNRNRNR
Tsega et al. [29]2386591NR115cNRNRNRNRNRNRNRNRNRNR
Mohammed and Ali [30]1174022NR3NRNR11NRNRNRNRNRNRNRNR
Abdelmenan et al. [31]81246713839NRNRNRNR117163NRNRNRNRNRNR
Orlien et al. [32]1505524NRNR1NR3NRNR2NRNRNR83
Orlien et al. ∗ [33]1505524NRNR133NRNR2NRNRNR80
Terefe Tesfaye et al. [34]109391271NRNRNR154111NRNR28
Bihonegn and Ayalewu [35]947315NRNRNRNRNR53NRNRNRNRNRNRNR

Assessed from a 358 participants, b 220 participants, c 65 participants. HIV: human immunodeficiency virus, NR: not reported, CLD: chronic liver disease, HBV: hepatitis B virus, HCV: hepatitis C virus NAFLD: nonalcoholic fatty liver disease.