Research Article
Prognostic Impact of Cirrhosis in Patients with Intrahepatic Cholangiocarcinoma following Hepatic Resection
Table 5
Subgroup analysis of cirrhotic patients (
).
| Variables | Overall survival | Relapse-free survival | Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | 1 yr | 5 yr | value | HR (95% CI) | value | 1 yr | 5 yr | value | HR (95% CI) | value |
| Resection type | | | | | | | | | | | Minor hepatectomy | 75.0 | 14.3 | 0.004 | 0.297 (0.051–1.746) | 0.179 | 50.0 | 11.1 | 0.019 | 0.402 (0.093–1.734) | 0.222 | Major hepatectomy | 44.4 | 0 | 22.2 | 0 | Tumor size | | | | | | | | | | | >5 cm | 27.3 | 0 | <0.001 | 16.435 (2.211–122.179) | 0.006 | 9.1 | 0 | <0.001 | 10.264 (1.881–55.987) | 0.007 | ≤5 cm | 92.9 | 20.0 | 64.3 | 14.3 | Lymph node metastasis | | | | | | | | | | | Present | 41.7 | 0 | 0.002 | 2.505 (0.595–10.536) | 0.210 | 16.7 | 0 | 0.007 | 2.345 (0.696–7.900) | 0.169 | Absent | 84.6 | 20.0 | 61.5 | 14.3 |
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HR: hazard ratio, CI: confidence interval.
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