Prognostic Impact of Cirrhosis in Patients with Intrahepatic Cholangiocarcinoma following Hepatic Resection
Table 1
Clinicopathological characteristics of the patients according to the presence of HBV infection and cirrhosis.
Variables
Overall patients ()
Group 1 ()
Group 2 ()
Group 3 ()
Group 4 ()
Age
Gender
Male
62 (58.5)
14 (93.3)
14 (51.9)
5 (50.0)
29 (53.7)
Female
44 (41.5)
1 (6.7)
13 (48.1)
5 (50.0)
25 (46.3)
Preoperative AFP
>9 ng/ml
28 (26.4)
8 (53.3)
9 (33.3)
2 (20.0)
9 (16.7)
≤9 ng/ml
78 (73.6)
7 (46.7)
18 (66.7)
8 (80.0)
45 (83.3)
Preoperative CA19-9
>35 U/ml
73 (68.9)
9 (60.0)
19 (70.4)
7 (70.0)
38 (70.4)
≤35 U/ml
33 (31.1)
6 (40.0)
8 (29.6)
3 (30.0)
16 (29.6)
Resection type
Minor hepatectomy
48 (45.3)
10 (66.6)
10 (37.0)
6 (60.0)
22 (40.7)
Major hepatectomy
58 (54.7)
5 (33.4)
17 (63.0)
4 (40.0)
32 (59.3)
Tumor size
>5 cm
61 (57.5)
7 (46.7)
21 (77.8)
4 (40.0)
29 (53.7)
≤5 cm
45 (42.5)
8 (53.3)
6 (22.2)
6 (60.0)
25 (46.3)
Tumor number
Single
89 (84.0)
13 (86.7)
23 (85.2)
9 (90.0)
44 (81.5)
Multiple
17 (16.0)
2 (13.3)
4 (14.8)
1 (10.0)
10 (18.5)
Child-Pugh score
A
100 (94.3)
13 (86.7)
26 (96.3)
9 (90.0)
52 (96.3)
B
6 (5.7)
2 (13.3)
1 (3.7)
1 (10.0)
2 (3.7)
Histologic grade
Well or moderate
52 (49.1)
5 (33.4)
12 (44.4)
4 (40.0)
31 (57.4)
Poor
54 (50.9)
10 (66.6)
15 (55.6)
6 (60.0)
23 (42.6)
Vascular invasion
Present
28 (26.4)
8 (53.3)
8 (29.6)
3 (30.0)
9 (16.7)
Absent
78 (73.6)
7 (46.7)
19 (70.4)
7 (70.0)
45 (83.3)
Lymph node metastasis
Present
48 (45.3)
6 (40.0)
9 (33.3)
6 (60.0)
27 (50.0)
Absent
58 (54.7)
9 (60.0)
18 (66.7)
4 (40.0)
27 (50.0)
Group 1, patients with HBV infection and cirrhosis; Group 2, patients with HBV infection but without cirrhosis; Group 3, patients with cirrhosis but without HBV infection; Group 4, patients without both HBV infection and cirrhosis; AFP, alpha-fetoprotein; CA19-9, carbohydrate antigen 19-9.
