Outcomes following Serial Intragastric Balloon Therapy for Obesity and Nonalcoholic Fatty Liver Disease in a Single Centre
Table 3
Anthropometric and ALT changes following serial IGB therapy.
Clinical parameter
After 1st IGB (T1)
After 2nd IGB (T2)
After 3rd IGB (T3)
p value
Final weight (kg)
107.9 ± 23.5
99.6 ± 17.1
97.9 ± 43.4
0.18
Incremental weight change
0.05
Total weight change
<0.01
Final BMI (kg/m2)
39.0
35.5
38.2
0.15
Total change in BMI
<0.01
Final HOMA-IR
4.27
1.89
2.71
0.21
Total change in HOMA-IR
0.71
Final ALT (IU/L)
31.7
27.9
26.3
0.57
Total change in ALT
21.8
<0.01
Total follow-up (months)
17.1
18.8
26.6
Final outcomes:
(i) Loss to follow-up
44
25
9
0.65
(ii) Referred for surgery
12
10
5
(iii) Still in active follow-up
11
13
6
Changes compared with the start weight prior to IGB insertion, and the end of the treatment period (T1/T2/T3). Changes compared with baseline (prior to placement of the 1st IGB), and final follow-up. Data only available in 5 cases. Significant changes were observed in outcomes between T1 and T2, but not between T2 and T3.
