Determination of Cutoff Values for the Screening of Osteosarcopenia in Obese Postmenopausal Women

Table 3

Comparison of cutoff values according to different methods.

Variables	ROC curve (N = 90)	Lowest 20th percentile (N = 118)	2SD below young reference group (N = 118)	Standard cutoff
FFMI (kg/m^2)	15.2	14.4	12.8	—
SMMI (kg/m^2)	8.2	7.6	6.7	—
AppSMMI (kg/m^2)	—	5.4	4.7	5.7^ƚ
Handgrip strength (kg)	16.5	16.0	11.4	18.0^ƚ
BUA (dB/MHz)	53.0	55.3	37.7	54.0^ƒ
SOS (m/s)	1492.15	1501.4	1458.8	—
Est. BMD (g/cm^2)	—	0.349	0.205	—
T-score (MY ref.)	—	−2.1	−3.5	−2.5^δ

ROC: receiver operating characteristic; SD: standard deviation; FFMI: fat-free mass index; SMMI: skeletal muscle mass index; appSMMI: appendicular skeletal muscle mass index; BUA: broadband ultrasonic attenuation; SOS: speed of sound; Est. BMD: estimated bone mineral density; MY: Malaysia. ^ƒJohansen, Evans, and Stone, 1999. ^ƚChen et al., 2014. ^δWorld Health Organization (WHO).