Predictors of Inappropriate Proton Pump Inhibitors Use in Elderly Patients
Table 1
Comparison of demographic and medical history differences between patients receiving PPIs without a proper indication and patients who were not receiving PPIs.
Demographic characteristics & Medical history
Patients receiving PPIs without a proper indication n=195 (25.7%)
Patients not receiving PPIs n=526 (74.3%)
Statistical significance
Gender
Males
94 (48.2%)
238 (45.2%)
NS
Females
101 (51.8%)
288 (54.8%)
Age (M±1SD) (years old)
80.0±7.9
80.4±8.0
NS
Age group
65-74 (years old)
51 (26.1%)
131 (24.9%)
NS
75-84 (years old)
83 (42.6%)
209 (39.7%)
≥85 (years old)
61 (31.3%)
186 (35.4%)
Katz index (95 CI)
3.36 (3.01-3.70)
3.88 (3.65-4.09)
p=0.01 (U=45328.00)
CCI (95 CI)
6.18 (5.90-6.46)
5.36 (5.18-5.54)
p ≤0.001 (U=37922.00)
Number of diseases (95 CI)
3.77 (3.56-3.99)
2.73 (2.59-2.86)
p ≤0.001 (U=33269.00)
Number of medications (95 CI)
6.03 (5.64-6.43)
4.10 (3.86-4.35)
p ≤0.001 (U=31218.50)
Blood thinner
Yes
111 (56.9%)
199 (37.8%)
p ≤0.001
No
84 (43.1%)
327 (62.2%)
(χ2=21.15)
NS: nonsignificant; CI: confidence interval; CCI: Charlson Comorbidity Index; mean ± 1 standard deviation.
