Research Article
Diagnostic Performance of Glymphatic System Evaluation Using Diffusion Tensor Imaging in Idiopathic Normal Pressure Hydrocephalus and Mimickers
| | Control | piNPH | iNPH | P values | (n = 12) | (n = 12) | (n = 12) | Control vs. piNPH | Control vs. iNPH | piNPH vs. iNPH |
| Age [years] | 75.7 ± 8.4 | 75.7 ± 9.4 | 75.3 ± 7.3 | 1 | 1 | 1 | Sex [Female, Male] | 6, 6 | 8, 4 | 4, 8 | 1 | 1 | 1 | Clinical symptoms | | | | | | | Gait disturbance [n] | 0 | 10 | 12 | < 0.001 | < 0.001 | 1 | Cognitive impairment [n] | 0 | 7 | 11 | 0.014 | < 0.001 | 0.465 | Urinary incontinence [n] | 0 | 7 | 10 | 0.014 | < 0.001 | 1 | Imaging indexes | | | | | | | Evans index [degree] | 26.9 ± 4.1 | 34.8 ± 3.4 | 37.2 ± 2.9 | < 0.001 | < 0.001 | 0.444 | Callosal angle [degree] | 126.8 ± 31.2 | 120.3 ± 35.5 | 87.7 ± 17.3 | 1 | 0.008 | 0.047 | Ventricular volume [mL] | 40.3 ± 16.1 | 127.5 ± 21.1 | 161.0 ± 22.4 | < 0.001 | < 0.001 | 0.032 | PVWH grade [n] | | | | | | | grade 3 | 0 | 1 | 0 | 0.071 | 0.314 | 0.916 | grade 2 | 0 | 3 | 2 | grade 1 | 3 | 5 | 5 | grade 0 | 9 | 3 | 5 |
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Note. Data are shown as mean ± standard deviation.
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