Mechanical Power in Prone Position Intubated Patients with COVID-19-Related ARDS: A Cohort Study

Table 2

Ventilatory settings and monitoring parameters during pre-, first-, and last-prone sessions.

Variables	Survivors	Nonsurvivors	value	Effects ( value)
				Survival	Time	Survival × time
Mechanical power (J/min)				0.004	0.004	0.009
Preprone	26.0 ± 2.34^a	29.2 ± 2.64^a	0.073
First prone	25.7 ± 2.0^a	26.9 ± 2.4^a	0.445
Last prone	26.0 ± 2.3^a	32.9 ± 2.8^b	<0.001
Ventilatory ratio				<0.001	<0.001	0.009
Preprone	2.0 ± 0.14^a	2.4 ± 0.2^a	<0.001
First prone	2.1 ± 0.16^ab	2.5 ± 0.17^a	<0.001
Last prone	2.2 ± 0.16^b	3.0 ± 0.24^b	<0.001
PaO2/FiO2 ratio				0.001	<0.001	0.001
Preprone	115.0 ± 4.0^a	117.0 ± 3.0^a	0.144
First prone	270.0 ± 20.0^b	202.0 ± 11.0^b	0.003
Last prone	283.0 ± 20.0^b	181.0 ± 11.0^b	<0.001
Driving pressure (cm H2O)				0.570	<0.001	0.467
Preprone	13.6 ± 0.45^b	13.6 ± 0.51^b	0.971
First prone	11.7 ± 0.5^a	12.3 ± 0.5^a	0.360
Last prone	11.6 ± 0.54^a	12.5 ± 0.78^ab	0.325
PEEP (cm H2O)				0.794	0.008	0.089
Preprone	12.0 ± 0.26^a	12.0 ± 0.4^b	0.929
First prone	12.0 ± 0.24^a	11.4 ± 0.39^a	0.185
Last prone	12.3 ± 0.33^a	12.6 ± 0.42^b	0.643
Tidal volume (ml/kg PBW)				0.842	0.435	0.397
Preprone	6.6 ± 0.13^a	6.8 ± 0.15^a	0.329
First prone	6.6 ± 0.12^a	6.7 ± 0.15^a	0.797
Last prone	6.5 ± 0.11^a	6.7 ± 0.14^a	0.378
Respiratory rate (mpm)				0.025	<0.001	0.482
Preprone	23.7 ± 3.6^a	25.2 ± 3.7^a	0.045
First prone	25.2 ± 3.4^a	26.2 ± 3^a	0.136
Last prone	25.8 ± 3.5^a	27.4 ± 3.7^a	0.04

PaO₂ = arterial oxygen pressure; FiO₂ = inspired oxygen; PEEP = end-expiratory positive pressure.Mean ± standard deviation. values adjusted by SAPS III, number of days on MV, and number of prone maneuvers and age; ^abequal letters do not differ by the least significant difference (LSD) test at 5% significance.