Research Article

Incidence and Impact of Ventilator Associated Multidrug Resistant Pneumonia in Patients with SARS-COV2

Table 1

Demographic and comorbidity distributions.

TotalVAPNo VAP

N14841107
Age, mean (years)6058.660.50.5
Sex, %
 Male, n (%)86 (58)26 (63)60 (56)0.4
 Female, n (%)62 (42)15 (37)47 (44)0.4
Race, %
 Black99 (70)24 (62)75 (74)0.2
 White10 (7)4 (10)6 (6)0.4
 Native American1 (1)0 (0)1 (1)
 Other31 (21)11 (28)20 (20)0.3
Ethnicity, %
 Hispanic30 (20)12 (32)18 (19)0.09
 Nonhispanic102 (69)26 (68)76 (81)0.4
Comorbidities, %
 Cancer29 (20)4 (10)25 (23)0.03
 Diabetes mellitus86 (58)27 (66)59 (55)0.2
 Heart disease95 (64)29 (71)66 (62)0.3
 Hypertension99 (67)25 (61)74 (69)0.5
 Immune disorder18 (12)4 (10)14 (13)0.6
 Chronic kidney disease23 (16)9 (22)14 (13)0.2
 Chronic liver disease24 (16)9 (22)15 (14)0.2
 Prior CVA7 (5)3 (7)4 (3)0.7
 BMI, mean32.934.232.40.3
Highest SOFA score within 48 hours of admission (mean)6650.4
Highest SOFA score prior to ICU admission (mean)1314130.03
Empiric antibiotic prior to IMV (%)60 (41)24 (59)60 (56)0.8
Empiric antibiotic within 48 hours of IMV (%)120 (81)36 (88)84 (79)0.2
Discharge disposition, n (%)
 Mortality81 (55)20, (49)61, (57)0.4
 Home40 (27)6, (15)34, (32)0.04
 Skilled facility28 (19)15, (37)13, (12)<0.001
ICU LOS, mean (d)203016<0.001
Hospital LOS, mean (d)223517<0.001

values by chi-squared or welch’s t-test. value calculated by chi-squared; value calculated by welch’s t-test P values by t-test for VAP by each variable. VAP–ventilator associated pneumonia; CVA–cerebrovascular accident; BMI–body mass index; SOFA–sequential organ failure assessment; IMV–invasive mechanical ventilation; ICU–intensive care unit; LOS–length of stay.