Utility of Pulse Oximetry Oxygen Saturation (SpO₂) with Incorporation of Positive End-Expiratory Pressure (SpO₂10/FiO₂PEEP) for Classification and Prognostication of Patients with Acute Respiratory Distress Syndrome

Table 3

Depiction of the predictive ability for survival for the various P/FP10 and S/FP10 ratios at different time intervals.

Variables	Cut-off value	AUC	value	Sensitivity (%)	Specificity (%)	95% CI
S/FP10 (B)	≥162	0.558	0.391	52	53	0.427–0.689
P/FP10 (B)	≥187.6	0.635	0.046	69	58	0.507–0.763
P/FP10 (D1)	176.8	0.534	0.618	55	53	0.401–0.666
S/FP10 (D1)	≥157.5	0.545	0.508	53	55	0.416–0.674
P/FP10 (D3)	≥257.5	0.900	<0.001	80	87	0.833–0.968
S/FP10 (D3)	≥243.75	0.872	<0.001	78	77	0.787–0.956
S/FP (D3-B)	≥64.40	0.877	<0.001	73.5	97	0.803–0.952
S/FP (D3-D1)	≥75.62	0.821	<0.001	71.4	80	0.728–0.914
P/FP (D3-B)	≥34.25	0.902	<0.001	81.6	90	0.834–0.970
P/FP (D3-D1)	≥28.56	0.876	<0.001	83.7	80	0.798–0.953

PaO₂ = partial pressure of arterial oxygen, SpO₂ = pulse oximetry oxygen saturation, FiO₂ = fraction of inspired oxygen, PEEP = positive end-expiratory pressure, P/FP10 = (PaO₂10)/(FiO₂PEEP), S/FP10 = (SpO₂10)/(FiO₂PEEP), P/FP10 (B) = the value obtained at one hour after intubation and initiation of MV, S/FP10 (B) = corresponding values obtained at one hour after intubation and MV, P/FP10 (D1) = worst values of P/FP10 day 1 (within 1–24 hours of intubation), S/FP10 (D1) = corresponding values of S/FP10 on day 1, P/FP10 (D3) = worst values of P/FP10 day 3 (within 48–72 hours of intubation), S/FP10 (D3) = corresponding values of S/FP10 on day 3 (within 48–72 hours of intubation), S/FP (D3-B) = change in S/FP10 from baseline to day three, S/FP (D3-D1) = change in S/FP10 from day one to day three, P/FP (D3-B) = change in P/FP10 from baseline to day three, and P/FP (D3-D1) = change in S/FP10 from day one to day three.