The Feasibility of Percutaneous Dilatational Tracheostomy in Immunosuppressed ICU Patients with or without Thrombocytopenia
Table 1
Baseline characteristics and data from ICU.
Baseline characteristics and data from ICU
Parameter
All patients
PDT patients
OST patients
value
Patients, n (%)
84 (100)
63 (75)
21 (25)
Female, n (%) per group
35 (41.7)
25 (39.7)
10 (47.6)
0.613
Age (y)
57.5 (49.3–67.8)
60 (51–68)
53 (43–63.5)
0.070
SAPS II
45.3 ± 13.6
47.4 ± 13.4
39.7 ± 10.9
0.084
Ventilation before PDT/OST (d)
13 (9–17)
13 (9–17)
12 (7–17)
0.472
Hematological/oncological disease, n (%)
46 (54.7)
39 (61.9)
7 (33.3)
0.156
AlloSCT, n (%)
19 (22.6)
16 (25.4)
3 (14.3)
0.033
Mucositis, n (%)
17 (20.2)
16 (25.4)
1 (4.8)
0.043
CTCAE grade 1, n (%)
7 (8.3)
7 (11.1)
0
0.133
CTCAE grade 2, n (%)
5 (6.0)
5 (7.9)
0
0.186
CTCAE grade 3, n (%)
5 (6.0)
4 (6.3)
1 (4.8)
0.791
CTCAE grade 4, n (%)
0
0
0
—
Solid organ transplant, n (%)
8 (9.5)
4 (6.3)
4 (19.0)
0.088
COVID-19, n (%)
11 (13.1)
11 (17.5)
0 (0)
0.041
Leucocyte counts (G/l)
9.88 (4.26–15.65)
8.58 (3.3.8–14.1)
11.5 (5.96–16.4)
0.273
Platelet counts (G/l)
92.5 (29–201)
86 (28–204)
125 (44–1195)
0.602
CTCAE grade 1, n (%)
13 (15.5)
9 (14.3)
4 (19.0)
0.524
CTCAE grade 2, n (%)
8 (9.5)
6 (9.5)
2 (9.5)
1.000
CTCAE grade 3, n (%)
12 (14.3)
10 (15.9)
2 (9.5)
0.699
CTCAE grade 4, n (%)
15 (17.9)
11 (17.5)
4 (19.0)
0.876
Anticoagulation with heparin, n (%)
17 (20.2)
13 (20.6)
4 (19.0)
0.876
Coagulopathy (ACLF), n (%)
7 (8.3)
7 (11.1)
0 (0)
0.113
Immunosuppression, n (%)
60 (71.4)
49 (77.8)
11 (52.4)
0.302
Antibiotic therapy, n (%)
80 (95)
60 (95.2)
20 (95.2)
0.095
Complications
Fracture of cartilage, n (%)
13 (20.6)
—
Stoma site infection, n (%)
13 (15.5)
5 (7.9)
8 (38.1)
0.427
CTCAE grade 1, n (%)
10 (11.9)
5 (7.9)
5 (23.8)
0.053
CTCAE grade 2, n (%)
3 (3.6)
0
3 (14.3)
0.002
CTCAE grade 3, n (%)
0
0
0
—
CTCAE grade 4, n (%)
0
0
0
—
Smears positive, n (%)
10 (11.9)
6 (9.5)
4 (19.0)
0.156
Bleeding postprocedural, n (%)
8 (9.5)
2 (3.2)
6 (28.6)
0.001
Length of stay in ICU (d)
32.5 (24–53)
34 (25–53)
31 (19–54)
0.423
The data are mean values ± standard deviation, median with interquartile range, or number of patients, and in brackets, the percentage of the respective group.
