The Prognostic Accuracy Evaluation of mNUTRIC, APACHE II, SOFA, and SAPS 2 Scores for Mortality Prediction in Patients with Sepsis
Table 1
Baseline clinical characteristics of patients.
Total (n = 194)
Survivors (n = 121)
Nonsurvivors (n = 73)
Value
Characteristics
Age, years
69 (59–80)
69 (59–78)
69 (57–83)
0.630
Male sex, n (%)
143 (73.7)
87 (71.9)
56 (76.7)
0.463
Septic shock, n (%)
141 (72.6)
79 (65.3)
62 (84.9)
0.002
Noradrenaline dose, μg/kg/min
0.18 (0.00–0.40)
0.10 (0.00–0.30)
0.25 (0.10–0.50)
0.477
Mechanical ventilation, n (%)
162 (83.5)
91 (75.2)
71 (95.9)
0.001
Length of ICU stay, days
5 (3–9)
5 (3–9)
5 (2–10)
0.724
Comorbidities
Hypertension, n (%)
78 (40.2)
47 (38.8)
31 (42.7)
0.620
Diabetes mellitus, n (%)
49 (25.3)
24 (19.8)
25 (34.2)
0.025
Stroke, n (%)
28 (14.4)
18 (14.8)
10 (13.7)
0.822
COPD, n (%)
10 (5.2)
3 (2.5)
7 (9.6)
0.061
Source of infection
Abdominal
86 (44.3)
68 (56.2)
18 (24.6)
Respiratory
82 (42.3)
42 (34.7)
40 (54.8)
Urinary tract
10 (5.2)
6 (4.9)
4 (5.5)
Skin
11 (5.7)
1 (0.8)
10 (13.7)
Other
5 (2.6)
4 (3.4)
1 (1.4)
Initial physiologic variables,
Heart rate, bpm
107 (90–120)
100 (90–120)
110 (100–120)
0.008
MAP, mmHg
73.0 (63.0–85.0)
75.5 (70.0–88.0)
70.0 (60.0–73.0)
0.001
Severity of illness
SOFA score
10 (6–12)
7 (5–11)
11 (10–14)
<0.001
APACHE II score
18 (13–23)
14 (11–20)
23 (19–27)
<0.001
SAPS 2 score
44 (34–56)
39 (39–47)
53 (42–61)
<0.001
mNUTRIC score
5 (4–6)
4 (3–5)
6 (5–7)
<0.001
mNUTRIC ≥5
116 (59.8)
51 (42.1)
65 (89.0)
<0.001
Data are introduced as median(interquartilerange) and number (n) of patients (%), as appropriate. COPD, chronic obstructive pulmonary disease; APACHE II, acute physiology and chronic health evaluation; ICU, intensive care unit; MAP, mean arterial pressure; mNUTRIC, modified Nutrition Risk in Critically Ill; SOFA, sequential organ failure assessment; SAPS 2, Simplified Acute Physiology Score 2; .
