Noninvasive Mechanical Ventilation with Average Volume-Assured Pressure Support versus BiPAP S/T in De Novo Hypoxemic Respiratory Failure
Table 4
Physiological and ventilator parameters in hypoxemic ARF from baseline to 1, 6, and 12 h on BIPAP-ST-AVAPS.
pH (mmhg), means ± SD
pH (Baseline)
pH (1 Hour)
pH (6 Hours)
pH (12 Hours)
Value
Failure
7.38 ± 0.05
7.40 ± 0.05
7.41 ± 0.04
7.40 ± 0.05
0.005
Success
7.44 ± 0.05
7.46 ± 0.06
7.45 ± 0.04
7.46 ± 0.02
pCO2 (mmhg), means ± SD
Pco2 (Baseline)
Pco2 (1 Hour)
Pco2 (6 Hours)
Pco2 (12 Hours)
Value
Failure
33.8 ± 5.2
33.4 ± 5.0
34.1 ± 5.8
32.3 ± 4.8
0.33
Success
30.2 ± 5.4
31.8 ± 4.5
30.6 ± 5.4
33.3 ± 5.8
pO2 (mmhg), means ± SD
Po2 (Baseline)
Po2 (1 Hour)
Po2 (6 Hours)
Po2 (12 Hours)
Value
Failure
77.5 ± 9.9
87.6 ± 20.6
99.4 ± 26.9
106.3 ± 41.2
0.001
Success
75.3 ± 12.5
104.9 ± 32.1
117.5 ± 34.1
126.6 ± 35
HCO3, (mmol/L) means ± SD
HCO3 (Baseline)
HCO3 (1 Hour)
HCO3 (6 Hours)
HCO3 (12 Hours)
Value
Failure
22.5 ± 4.4
23 ± 5.5
24.5 ± 7.1
20.8 ± 5.2
0.2
Success
21.6 ± 4.4
23.3 ± 5.1
23.6 ± 4.4
25.7 ± 3.5
FiO2 (%), means ± SD
Fio2 (Baseline)
Fio2 (1 Hour)
Fio2 (6 Hours)
Fio2 (12 Hours)
Value
Failure
0.42 ± 0.04
0.44 ± 0.08
0.52 ± 0.09
0.53 ± 0.10
0.001
Success
0.42 ± 0.04
0.39 ± 0.04
0.36 ± 0.06
0.34 ± 0.04
PaO2/FiO2 (mmHg)
Pao2/Fio2 (Baseline)
Pao2/Fio2 (1 Hour)
Pao2/Fio2 (6 Hours)
Pao2/Fio2 (12 Hours)
Value
Failure
185.3 ± 32.8
204.1 ± 67.2
197.0 ± 7 8.6
219.6 ± 148.4
0.001
Success
180.2 ± 35
269.2 ± 87.9
327.9 ± 106.1
340.4 ± 95.5
= statistical significance. PCO2: partial pressure of carbon dioxide; PO2: partial pressure of arterial oxygen; HCO3: bicarbonates; FiO2: inspired fraction of oxygen; PaO2/FiO2: ratio of partial arterial oxygen pressure and inspired fraction of oxygen.
