Ketamine Boluses Are Associated with a Reduction in Intracranial Pressure and an Increase in Cerebral Perfusion Pressure: A Retrospective Observational Study of Patients with Severe Traumatic Brain Injury

Figure 1

Change in ICP after ketamine bolus according to baseline ICP values. The blue circles represent patients without decompressive surgery, whereas the red circles are those with decompressive surgery. The bold lines are the regression lines (black for the whole population and red and blue for those with and without decompressive surgery, respectively), whereas the dashed lines are the 95% confidence intervals around the regression lines. The gray zone represents events where the ICP decreased the greatest according to the regression model.