Prolonged ICU Stay in Severe and Critically-Ill COVID-19 Patients Who Received Convalescent Plasma Therapy

Table 2

Bivariate analysis of variables.

Variable	Deceased		LOS <7 days		No O2 support device improvement
Convalescent plasma-n (%)
Yes	23 (47.9)	0.23	12 (25.0)	<0.001	20 (41.6)	0.16
No	76 (58.0)		76 (58.0)		40 (30.5)
Age group-n (%)
<45 years	22 (43.1)	0.04	29 (56.8)	0.194	18 (35.3)	0.75
>45 years	77 (60.2)		59 (46.1)		42 (32.8)
Hypertension-n (%)
Yes	38 (65.5)	0.058	21 (36.2)	0.017	21 (36.2)	0.598
No	61 (50.4)		67 (55.3)		39 (32.2)
Diabetes mellitus-n (%)
Yes	44 (57.9)	0.549	35 (46.0)	0.475	26 (34.2)	0.398
No	55 (53.4)		53 (51.4)		34 (33.0)
Obesity-n (%)
Yes	17 (68.0)	0.173	13 (52.0)	0.759	3 (12.0)	0.02
No	82 (53.2)		75 (48.7)		57 (37.0)
Mechanical ventilation on admission-n (%)
Yes	67 (84.8)	<0.001	39 (49.3)	0.96	16 (20.2)	0.001
No	63 (4.5)		49 (49.0)		44 (44.0)
Mechanical ventilation during ICU stay-n (%)
Yes	96 (84.9)	<0.001	51 (44.0)	0.159	20 (17.7)	<0.001
No	47 (35.9)		37 (56.0)		40 (60.6)
WBC^1 count >11 × 10^9/L-n (%)
Yes	57 (66.2)	0.005	49 (57.0)	0.045	25 (29.0)	0.23
No	42 (45.1)		39 (41.9)		35 (37.6)
Neutrophil-Lymphocyte ratio >11-n (%)
Yes	61 (67.7)	<0.001	46 (51.1)	0.6	23 (25.5)	0.08
No	38 (42.7)		42 (47.2)		37 (41.5)
PaO2/FiO2 ratio <200-n (%)
Yes	89 (61.8)	<0.001	65 (45.1)	0.031	43 (29.8)	0.038
No	10 (28.5)		23 (65.7)		17 (48.6)
D-dimer (ng/mL) >1000 ng/mL-n (%)^2
Yes	74 (62.7)	0.006	61 (51.7)	0.35	35 (29.7)	0.13
No	25 (40.9)		27 (44.3)		25 (50.0)
Creatinine serum >1.2 mg/dL-n (%)
Yes	48 (76.1)	<0.001	31 (49.2)	0.99	13 (20.6)	<0.001
No	51 (43.9)		57 (49.1)		47 (40.5)
Random blood glucose >200 mg/dL-n (%)
Yes	54 (69.2)	0.001	38 (48.7)	0.92	20 (25.6)	0.051
No	45 (44.5)		50 (49.5)		40 (39.6)

¹WBC: white blood cells. ²Baseline D-dimer was measured in 48 (100%) patients in plasma group and 122 (93%) patients in control group.