Research Article

Heart-Protective Mechanical Ventilation in Postoperative Cardiosurgical Patients

Table 1

Changes in respiratory parameters in patients from the interventional group at three hours of the study, median (25th; 75th percentiles), n = 95.

DataHours in ICU
#1#2#3

MV (l × min−1)11.2 (10.1; 12.6)6.4 (5.8; 7.2)6.7 (6.1; 7.6) <0.001

Va (l × min−1)9.5 (8.8; 10.7)5.4 (5.0; 6.1)5.2 (4.7; 5.9) <0.001

(cmH2O)10.0 (10.0; 11.0)8.0 (8.0; 9.0)13.0 (13.0; 14.0) <0.001

(cmH2O)21.0 (20.0; 23.0)21.0 (19.0; 22.0)21.0 (19.0; 23.0) = 0.5
 = 0.06
<0.001

R (cmH2O × l−1 × sec−1)7.9 (6.5; 8.5)7.4 (6.4; 8.6)7.0 (6.0; 8.0) <0.001
 = 0.007

С (ml × cmH2O−1)54.1 (46.7; 62.1)56.7 (49.0; 62.4)54.1 (48.2; 59.8) = 0.2
<0.001
 = 0.006

Vds/Vte (%)14.0 (12.0; 15.0)14.0 (13.0; 16.0)21.0 (18.0; 24.0) <0.001
 = 0008

ΔP (cmH2O)16.0 (15.0; 18.0)16.0 (14.0; 17.0)11.0 (9.0; 13.0) <0.001

MV: minute ventilation; Va: alveolar ventilation; : mean airway pressure; : inspiratory pressure; R: resistance; C: compliance; Vds/Vte: dead space/tidal volume ratio; ΔР: driving pressure; P: Wilcoxon test.