Research Article

Prevalence, Risk Factors, and Outcomes of Platelet Transfusion Refractoriness in Critically Ill Patients: A Retrospective Cohort Study

Table 5

Outcomes of patients by platelet refractory status based on the platelet increment (<10000 × 106/L) definition.

Total (N = 259)Yes (N = 142)No (N = 117) value

ICU mortalityN (%)153 (59.1)86 (60.6)67 (57.3)0.55
Hospital mortalityN (%)189 (73.0)105 (73.9)84 (71.8)0.70
New tracheostomy/238 patientsN (%)25 (10.9)19 (14.4)6 (6.1)0.046
Duration of mechanical ventilation (days)/238 patientsMedian (Q1, Q3)10.0 (6.0, 17.0)10.0 (5.0, 15.8)12.0 (6.0, 19.5)0.15
ICU length of stay (days)Median (Q1, Q3)13.0 (7.0, 23.0)16.0 (8.0, 26.0)12.0 (6.0, 21.0)0.02
Hospital length of stay (days)Median (Q1, Q3)28.0 (16.0, 58.0)33.0 (16.0, 62.5)27.0 (14.0, 47.0)0.11

For patients with missing data, the denominator is the number of patients with valid observations. For the calculation of percentages, only valid observations are used in the numerator and denominator. ICU: intensive care unit, Q1: first quartile, Q3: third quartile.