Critical Care Research and Practice

Research Article

Contribution of Levosimendan in Weaning from Mechanical Ventilation in Patients with Left Ventricular Dysfunction: A Pilot Study

Table 1

Clinical characteristics of the patients according to the first SBT outcome.


	First SBT ()		value
	Successful ()	Failed ()	value

Age (years)	74 ± 8	72 ± 9	0.6
Females (%)	2 (25)	4 (36)	0.9
MIP (cmH₂O)	−46 ± (−13)	−32 ± (−10)	0.02
Troponin (pg/ml)	432 ± 576	217 ± 268	0.36
NT-proBNP (pg/ml)	1564 ± 862	7515 ± 13643	0.36
Systolic BP (mmHg)	129 ± 25	123 ± 18	0.57
Diastolic BP (mmHg)	63 ± 15	60 ± 15	0.59
Heart rate (bpm)	91 ± 18	83 ± 15	0.31
SaO₂ (%)	99 ± 1	98 ± 1	0.69
PaO₂ (mmHg)	125 ± 26	132 ± 40	0.68
PaCO₂ (mmHg)	36 ± 5	38 ± 10	0.63
pH	7.41 ± 0.02	7.42 ± 0.04	0.69
ScvO₂ (%)	66 ± 8	66 ± 7	0.9
Hct (%)	25.7 ± 3.7	28.8 ± 4.3	0.1
48-hour fluid balance (mL)	371 ± 1134	618 ± 1646	0.72

No. of patients with
Ischemic heart disease, n (%)	4 (50)	9 (81)	0.32
Heart failure, n (%)	4 (50)	11 (100)	0.02
Hypertension, n (%)	7 (88)	11 (100)	0.42
Atrial fibrillation, n (%)	3 (38)	2 (18)	0.62
Diabetes mellitus, n (%)	3 (38)	4 (36)	0.90
Chronic kidney disease, n (%)	3 (35)	5 (45)	0.90
COPD, n (%)	2 (25)	3 (27)	0.90

SBT, spontaneous breathing trial; MIP, maximum inspiratory pressure; BP, blood pressure; NT-proBNP, N-terminal probrain natriuretic peptide; bpm, beats per minute; SaO₂, arterial oxygen saturation; PO₂, arterial oxygen tension; PaCO₂, arterial carbon dioxide tension; pH, arterial pH; ScvO₂, central venous oxygen saturation; Hct, haematocrit; COPD, chronic obstructive pulmonary disease; (), before the start of the first SBT.