Review Article
Renal Replacement Therapy in the Critical Care Setting
Table 4
Comparison of various RRT modalities.
| | IHD | SLED | CRRT |
| Cost | + | ++ | ++++ | Duration | 4 hrs daily /alternate days | 6–12 hrs daily /alternate days | 24 hrs (though achieves 16 hrs on avg.) Continuous | Haemodynamic instability | Least suitable | Good | Most compatible | Compatible with extracorporeal life support | No | No | Yes | In raised intracranial pressure | Increases | Can increase | Usually no change | Anti-coagulation | Can be omitted | Can be omitted | Predilution can be utilised to maintain circuit | Serum concentration of renally cleared drugs | Major fluctuations | Some fluctuation | Least fluctuation | Vascular access | AV fistula or nontunnelled or tunnelled catheter | AV fistula or nontunnelled or tunnelled catheter | Nontunnelled or tunnelled catheter | Compatible with supporting large volume infusions (antibiotics, nutrition, etc.) | No | Would need to be daily and longer sessions | Most compatible | Mobilisation | Most compatible | Could be compatible if done at night/rest time | Not compatible—would need to be discontinued. |
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IHD : intermittent haemodialysis; SLED : sustained low-efficiency dialysis; CRRT : continuous renal replacement therapy.
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