Research Article

Clinical Survey of Decreased Blood Flow Rate in Continuous Renal Replacement Therapy: A Retrospective Observational Study

Table 1

Clinical characteristics of the 119 enrolled patients.

Clinical characteristics

Age (years)7160–78
Male (n, %)8369.7
Height (cm)163.0155.5–170.0
Body weight (kg)60.051.4–70.0
BMI (kg/m2)22.620.0–26.0
Diabetes mellitus (n, %)4134.4
SBP (mmHg)9883–119
DBP (mmHg)5846–64
HR (/min)9380–113
Intubation (n, %)4235.3
SOFA score1210–15
Diagnosis at the time of starting CRRT
 Sepsis or severe infectious diseases (n, %)3932.8
 Heart failure (n, %)3428.6
 After cardiovascular surgery (n, %)2521.0
 Hepatic failure (n, %)21.7
 Mainly renal failure (n, %)54.2
 Tumor lysis syndrome (n, %)21.7
 Others (n, %)1210.1
Laboratory data
 Alb (g/dL)2.52.1–3.0
 Hb (g/dL)10.68.8–12.5
 CRP (mg/dL)9.94.3–18.8
Details of catheter
 Triple lumen catheter (n, %)8773.1
Catheter position
 Femoral vein (n, %)9579.8
 Jugular vein (n, %)2420.2
Condition of CRRT
Mode of CRRT
 CVVHDF (n, %)10084.0
 CVVHD (n, %)1916.0
Type of hemofilter
 PMMA (n, %)5142.9
 CTA (n, %)5445.4
 PS (n, %)108.4
 PES (n, %)32.5
 Others (n, %)10.8
ACT (sec)282243–350
Clinical outcome
 Decrease in the blood flow rate (n, %)5243.7
 Catheter-related bloodstream infection (n, %)2016.8
 All-cause death during CRRT (n, %)5546.2
 All-cause death during hospitalization (n, %)6252.1
Physician who inserted hemodialysis catheter
 Nephrologist (n, %)6655.5
 Over 10 years of experience (n, %)5243.7

Continuous variables are presented as the median and interquartile range. Categorical variables are presented as number (n) and frequency (%). ACT, activating coagulation time; Alb, albumin; BMI, body mass index; CRP, C-reactive protein; CRRT, continuous renal replacement therapy; CTA, cellulose triacetate; CVVHD, continuous venovenous hemodialysis; CVVHDF, continuous venovenous hemodiafiltration; DBP, diastolic blood pressure; Hb, hemoglobin; HR, heart rate; PES, polyethersulfone; PMMA, polymethylmethacrylate; PS, polysulfone; SBP, systolic blood pressure; SOFA score, sequential organ failure assessment score.