Clinical Study

The Microcirculation Is Unchanged in Neonates with Severe Respiratory Failure after the Initiation of ECMO Treatment

Table 3

Microcirculatory values.

T1 ECMOT2 ECMOT1 ControlsT2 Controls value at baseline* value over time

FCD [cm/cm2]4.5 (2.4–7.7)4.3 (2.8–7.4)5.0 (1.8–7.2)2.4 (1.4–4.2)0.811<0.001
MFI Large2.76 (2.50–3.00)2.88 (2.34–3.00)2.92 (2.50–3.00)3.00 (2.63–3.00)0.2660.367
MFI Medium2.67 (2.13–3.00)2.75 (2.13–3.00)2.75 (2.38–3.00)2.81 (2.50–3.00)0.2540.411
MFI Small2.75 (2.06–3.00)2.75 (2.08–3.00)2.88 (2.44–3.00)2.90 (2.63–3.00)0.5740.090
HI Large0.10 (0.00–0.30)0.09 (0.00–0.40)0.09 (0.00–0.29)0.00 (0.00–0.26)0.9510.2406
HI Medium0.14 (0.00–0.60)0.11 (0.00–0.35)0.10 (0.00–0.51)0.00 (0.00–0.27)0.7360.2421
HI Small0.18 (0.00–0.73)0.09 (0.00–0.37)0.09 (0.00–0.40)0.00 (0.00–0.17)0.5790.0971

Data are presented as median and range.
*Intergroup differences at T1 were assessed using Mann-Whitney test. For the time-dependent variables, differences at T2 were assessed using ANCOVA with the baseline measurement as covariate.
FCD: functional capillary density, MFI: microvascular flow index, HI: heterogeneity index.