Revolutionary advances in biochemistry in the last quarter century have significantly provided incredible opportunity for systematic approaches to understand many human disease processes from aging to cancer.

Despite these scientific achievements, the complex nature of cancer still remains a profound mystery. Therefore, further research to identify and characterize biochemical pathways that lead to changes in cell behavior that occur as cancer develops should be given high priority to improve knowledge of human health.

We invite scientists to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand how these biochemical pathways/processes change during cancer development and how such processes offer opportunities for prevention, screening, and treatment intervention of cancer.

In this special issue, we are interested in articles that explore various aspects of biochemical pathways that contribute to cancer initiation, promotion, and progression to metastasis. Potential topics include, but are not limited to:

• Biochemical pathways driving cancer etiology
• Biochemical alterations during tumorigenesis
• Novel biochemical tumor markers and selective inhibitors
• Tumor recurrence and chemoresistance

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/bcri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: