Cardiomyopathies: Classification, Clinical Characterization, and Functional Phenotypes
1Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL, USA
2Department of Basic Medicine, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan
3Department of Neurobiology, Physiology and Behavior, University of California, Oakland, CA, USA
4Department of Physiology and Biophysics, School of Medicine, Boston University, Boston, MA, USA
Cardiomyopathies: Classification, Clinical Characterization, and Functional Phenotypes
Description
Worldwide cardiovascular diseases (CVDs) are the leading cause of death with heart failure being highly prevalent in most affluent parts of the world. Despite significant clinical advances in the treatment of CVD, mortality rates remain high. Cardiomyopathy is a category of disorders that affects the cardiac muscle and can cause extensive disability in a large and ethnically diverse population. Cardiomyopathy has been classified by the World Health Organization into three main types, based on anatomical and physiological features: dilated (DCM), hypertrophic (HCM/FHC), and restrictive (RCM). It is becoming evident that the most promising approaches to alleviate or reverse detrimental disease phenotypes must emerge from target-specific interventions determined by the functional phenotype.
We invite authors to submit original research and review articles that seek to enhance the knowledge on cardiomyopathies, etiology, clinical, and functional phenotypes, as well as basic and translational research advances. Potential topics include, but are not limited to:
- Genetics and genomics of cardiomyopathies: FHC, DCM, and RCM
- Molecular and cellular mechanisms involved in cardiomyopathies
- Progression to heart failure
- Myofilament proteins: disease-causing mutations
- Animal models of FHC, DCM, and RCM
- Hypertrophic signaling pathways
- Contractility and calcium handling
- Energy consumption and metabolism
- Imaging techniques
- Cardiac regeneration, stem cells, and tissue engineering
Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/bcri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: